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Foreskin Surface Area And HIV Acquisition: Size Matters
April 08th, 2010
Randomized clinical trials conducted by researchers in Rakai, Uganda, have revealed a link between the size of foreskin surface area and the risk of male HIV acquisition. The results of the trials have been published in the current issue of AIDS, the leading journal in the field of HIV and AIDS research. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, and pharmacy.
In recent years, several studies have shown that circumcision reduces the risk of male HIV acquisition by 50-60%, and circumcision is now recommended by WHO/United Nations Joint Programme on HIV/AIDS (UNAIDS) as an HIV prevention strategy. Based on this evidence that the foreskin increases vulnerability to HIV, Dr Godfrey Kigozi and his colleagues hypothesized that the size of the foreskin might be related to the risk of HIV infection.
Eligible candidates for this retrospective cohort study were drawn from the initially HIV-negative participants in the Rakai Community Cohort Study. These men were subsequently enrolled into the randomized trials of male circumcision and had measurement of their foreskin surface area taken following surgery. The researchers then determined HIV acquisition in these men and assessed the association between foreskin size measured after surgery, and the incidence of HIV acquisition while under surveillance prior to circumcision. Their results determined that the risk of male HIV acquisition was significantly increased in men with larger foreskin surface areas.
The researchers point out that their study is unique and their findings therefore need to be replicated. However, these results, in addition to the observational studies and randomized trials, add plausibility to the hypothesis that the foreskin is a tissue vulnerable to HIV acquisition.
About AIDS
AIDS publishes the very latest ground breaking research on HIV and AIDS. Read by all the top clinicians and researchers, AIDS has the highest impact of all AIDS-related journals. With 18 issues per year, AIDS guarantees the authoritative presentation of significant advances. The Editors, themselves noted international experts, are committed to making AIDS the most distinguished and innovative journal in the field.
About Lippincott Williams & Wilkins
Lippincott Williams & Wilkins (LWW) is a leading international publisher for healthcare professionals and students with nearly 300 periodicals and 1,500 books in more than 100 disciplines publishing under the LWW brand, as well as content-based sites and online corporate and customer services.
LWW is part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals and institutions in medicine, nursing, allied health and pharmacy. Major brands include traditional publishers of medical and drug reference tools and textbooks, such as Lippincott Williams & Wilkins and Facts & Comparisons®; and electronic information providers, such as Ovid®, UpToDate®, Medi-Span® and ProVation® Medical.
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Wolters Kluwer Health
Financial Times To Launch Special Report On ‘Combating AIDS’ With Contribution To Global Business Coalition
April 08th, 2010
The Financial Times announces the launch of its special report ‘Combating AIDS.’ The supplement will be distributed in all global editions of the FT on Tuesday 1st December 2009, to coincide with World AIDS Day.
Following the success of the FT special report on ‘Combating Malaria,’ published in April 2009, ‘Combating AIDS’ is the second in a series of FT reports on major diseases. ‘Combating Tuberculosis’ and a second installation of ‘Combating Malaria,’ will be published to coincide with international fundraising campaigns and awareness days in 2010.
‘Combating AIDS’ will include the following features:
– A look at the principal causes and transmission routes of the disease
– An analysis of the pandemic’s impact on individuals and societies worldwide
– An exploration of how corporations have responded to the AIDS crisis, including specific case studies
– A look at the role education, awareness and advocacy programs will continue to play in shaping effective anti-AIDS initiatives
– A examination of the scientific and pharmaceutical responses to AIDS, including a look at the latest developments in vaccines, drugs and diagnostic processes
The FT will donate a portion of the proceeds from this special report to the Global Business Coalition (GBC) to fund the NGO’s efforts to fight HIV/AIDS, tuberculosis and malaria.
“The Financial Times realizes the vital need to devote its global scope and editorial insight to better understanding and combating the AIDS epidemic,” said Andrew Sollinger, Managing Director of the FT’s US Commercial Operations. “We are pleased to combine these efforts with the Global Business Coalition, an organization that effectively brings together leaders in the public and private sectors to improve public health.”
“The fight against HIV/AIDS cannot be won without the corporate sector stepping up and playing an active role. This is a business story, and it’s fitting that a business newspaper read by high-level corporate leaders is making this part of its editorial agenda,” said John Tedstrom, President and CEO of the Global Business Coalition. “We’re pleased that FT has once again demonstrated its commitment to keeping AIDS, and its impact on public health and economic development, a top-line issue for the corporate community. It’s a major asset in our global fight.”
About the Financial Times:
The Financial Times, one of the world’s leading business news organisations, is recognised internationally for its authority, integrity and accuracy. Providing extensive news, comment and analysis, the newspaper is printed at 23 print sites across the globe, has a daily circulation of 408,544 (ABC figures, September 2009) and a readership of 1.3 million people worldwide. FT.com is the definitive home for business intelligence on the web, providing an essential source of news, comment, data and analysis for the global business community. FT.com attracts 11.4 million unique users, generating 83.2 million page views (ABCe figures, March 2009) and now has over 1.6 million registered users.
About Global Business Coalition on HIV/AIDS, TB and Malaria:
The Global Business Coalition on HIV/AIDS, Tuberculosis and Malaria is a coalition of more than 220 companies united to keep the fight against these epidemics a global priority. The Coalition provides tailored support so that companies can take an active role in defeating the pandemics. The Coalition also organizes collective actions among companies and links the public and private sectors in ways that pool talents and resources. The official focal point of the private sector delegation to the Global Fund to Fight AIDS, Tuberculosis and Malaria, the Coalition maintains offices in New York, Paris, Johannesburg, Beijing, Nairobi and Moscow.
Source: Financial Times